Mastermind Genomic Intelligence Platform
The Most Comprehensive Source of Published Genomic Evidence
Designed for Genomic Scientists
Reduce Turnaround Time
Quickly identify and review the empirical evidence, clinically prioritized with insight into each article to speed variant interpretation
Increase Diagnostic Yield
Access 100X more genomic evidence and 20X more variants than other sources to find relevant articles, resolve more VUSs, and diagnose more patients
Accelerate Throughput
Optimize your workflow by automating the acquisition and prioritization of genetic evidence with the Mastermind API, supporting NCBI’s PubMed
Trusted by 20,000+ Users in 140+ Countries
Are you confident you have all the information you need for variant interpretation?
A 2020 Study reported that laboratories disagreed on a variant’s classification 46% of the time, with 23% of those discrepancies being clinically impactful. Access to comprehensive evidence is critical for proper diagnosis.
Why is searching for genomic literature so hard?
Legacy Nomenclature Makes Evidence Hard to Find
More than 74% of the genomic variants in publications are still in non-normalized forms1, making citations hard to find, even in resources like NCBI’s PubMed
Data is Hidden in the Body and Supplemental Text
Fewer than 6% of variants are identified in the title or abstract in NCBI’s PubMed, the remainder present in the full-text or supplemental files1.
Mastermind in Action
"I don’t consider a patient’s report complete unless every variant has been researched through Mastermind."
Nikoletta Sidiropoulos, MD
University of Vermont Health Network
"Using Mastermind enhances our ability to provide clinicians at the bedside with important relevant information about known treatments and interventions."
Stephen Kingsmore, MD DSc
Rady Children’s Institute for Genomic Medicine
"I can say with certainty that without the findings obtained from Mastermind, I would not have been able to provide a diagnosis for my patient."
Lipika Ray, PhD
Rare Genomics Institute
Be confident in the comprehensiveness of your evidence.
