Integrate comprehensive data into your pipeline
Comprehensive solutions providing insights at the gene and the variant level.
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Genomenon Data
Ensuring maximal accuracy and optimal sensitivity of your diagnostic interpretation pipeline
Be Data Driven
Get insights into associations between genes and diseases.
Save Time
Get comprehensive curated insights at the variant level, following ACMG guidelines.
Be Thorough
Access maximum sensitivity to reference articles using the Mastermind link.
Mastermind Data Files
Access comprehensive data that includes expertly curated gene and variant-level content with indexed variant-level data.
Curated Gene File
The Curated Gene File contains comprehensive information on over 9,000 gene-disease relationships across 6,500 genes. This file is updated on a monthly cadence and is the result of a scientific, data-driven approach by the Genomenon team, which includes a thorough review of external publications, clinical evidence, functional evidence, and more to determine classification and inheritance patterns, providing a trusted resource for understanding gene-disease relationships
Curated Variant File
This Curated Variant File provides an extensive repository of variant data for over 500 genes, adhering to ACMG guidelines to facilitate in-depth variant-level analysis for researchers. When combined with the curated gene file, it offers a unified and comprehensive platform, empowering users to access all the necessary information to interpret variants and supporting evidence in one place
Indexed Variant File
The Indexed Variant File offers highly detailed and sensitive information about genetic variants, updated quarterly for maximum accuracy. This comprehensive resource enables researchers to access variant-level data with precision, ensuring they don't miss crucial information in order to make informed decisions
Indexed Data [API]
Streamline your research workflow with automated evidence collection and real-time updates.
Access information from over 24,000,000 variants, 25,000 genes, 15,000 phenotypes, 69,000 drug therapies, and growing.
The Indexed Data API unlocks article insights, empowering users to standardize and prioritize variants of interest with ease, automate VCF annotation and complex time-based analyses, and support organizational capabilities including internal database updates.
Leveraging the Indexed Data [API] clients can ensure that they have the most up-to-date information, streamlining workflows and expediting analyses.
Standardization, Automation & Variant Prioritization
Automate evidence querying speeding their analyses and enables researchers to only analyze variants of interest
VUS Reanalysis
Retrieve updated evidence at your cadence intervals and based on specific criteria such as time
Support Internal Database Updates
Get PMIDs and article metadata after manual curation to support internal databases
Cancer Knowledgebase (CKB) FLEX Data
CKB is a valuable resource that can be utilized to interpret somatic variants and identify the most relevant therapy via efficacy evidence annotations. With CKB FLEX, users have access to scalable and flexible content for 2,000+ genes.
CKB Flex
- Get the information you need on therapeutic treatments. Easily mine curated content for drugs with clinical and preclinical evidence to gain insights into treatment options and access real-time clinical trial information for oncologists and patients
- You can also view resistance data for targeted therapies to assist with monitoring response, identify clinical areas lacking research evidence, and see the connections to growing data complexity with genomic signatures
- In addition, utilize translational model data to identify the models best suited for research and interrogate clinically actionable genes for gene panel design. With FLEX, users can also interpret data from NGS assays, liquid biopsies, and expression studies, and quickly locate genomic variants with biochemical functional effect
Talk to a Genomenon expert.
